27 Nov 2015

What is Glioblastoma Multiforme‬ and what are Treatments Available?

A rapidly growing tumor in the brain or spinal cord is known as Glioblastoma multiforme. This tumor affects the brain more compared to the spinal cord. These cancerous cells grow from glial cells, which is a supportive tissue of the brain and spinal cord. Another name for Glioblastoma multiforme is Glioblastoma, or grade 4 glioblastoma. The tumor growth may press against or damage nerves & structures in the brain. It interferes with the normal functioning of the brain.


A tumor may disrupt:
  • ·        Emotion 
  •      Thought 
  •      Vision 
  •      Hearing  
  •      Memory
  •      Movement 
  •      Touch
The swelling and fluid build-up in the brain can affect normal brain function. The various associated symptoms are:
  • Memory loss
  • Seizures 
  • More frequent Headaches
  • Nausea 
  • Vomiting  
  • Mood swings
  • Changes in personality 
  • Loss of concentration 
  • Changes in speech, vision, or hearing

    Lioblastoma multiforme life expectancy depends upon the person and severity of disease. But in most cases, such patients has very short life expectancy.

If any of these symptoms are occurring more, seek a medical help immediately. The doctor will diagnose you according to the symptoms and the history of past illnesses and treatments. He may check your reflexes, coordination, feeling or touch senses, pain response and muscle strength.

With Magnetic resonance imaging and Computed tomography doctor may be able to trace out the area of tumor. Positron emission tomography makes use of radioactive substances to see the functioning of how organs and tissues. Magnetic resonance spectroscopy looks at biochemical processes in the brain.




As per now glioblastoma is not curable. The aim of the treatment is to alleviate the symptoms such as pain relief, improve quality of life and prolong survival. The treatment of glioblastoma includes surgery, radiation, and chemotherapy. The surgeon will remove the tumor to relieve symptoms of glioblastoma multiforme.  He may perform a biopsy to confirm the diagnosis and the tissue that has been affected. This type of tumor grows in a tentacle form into surrounding brain tissue, which is not feasible to remove it completely. So the doctor chooses additional therapy such as radiation, External beam radiation therapy, Proton therapy and chemotherapy to destroy the remaining cancer cells.

Radiation make use of high beam of x-ray beams to shrink or to stop cancer growth, it is an immediate treatment after biopsy or surgery. Also read after surgery tips

In external beam radiation therapy the high power x rays are shot at the brain tumor and affected tissues. This is done from outside the body.

In brachytherapy, the radioactive substances are implanted directly into a tumor and then radiation is given to destroy the tumor.

The Proton therapy is performed on the patients with glioblastoma stage 4. It provides pinpoint or exact focusing of the radiation beam to the tumor, which minimizes the chance of surrounding normal brain tissue damage.

Certain drugs are used in Chemotherapy to stop the growth of cancer cells. Chemotherapy can be taken orally or intravenously or through muscle, or placed directly into a body part.

Remember that if you are experiencing any of these above symptoms, contact a medical professional immediately.

Patients from across the world can happily connect with IndianMedTrip to seek expert medical opinions from the top surgeons in India about the Glioblastoma multiforme treatment. The hospitals associated with Indianmedtrip are internationally accredited that render world-class medical facilities and special personalized care. Associated doctors and surgeons are highly qualified and skilled in their respective specialty. The IndianMedTrip medical tourism package includes post or preoperative consultation with doctors,  surgery appointment, accommodation, travel and sightseeing. 

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